Either have fun, or try practicing how to maneuver. If you happen to pick up something you shouldn’t have, you might just finish the run. I like to compare it to Ultra Hard in a way, where while you couldn’t gain health, at least it wasn’t like “Oh you picked up a heart? You lost”. Otherwise, you can try to go for angel rooms, they might have some really good stuff if they show up which won’t cost you anything (maybe a key if the game is cruel and places a lock in front). If it happened early I must have had a red heart for trade. I usually tried to pass on Devil Rooms unless something really good (usually 2 heart deals, but now always) came up, like Brimstone or The Pact. Goat Head can be amazing, given the circumstances (Angel rooms can have useless items while in Devil room you might not have hearts to trade away).ĭevil or Angel? Your choice. Range items are really good for Azazel, especially to deal with exploding enemies. Items that trigger on taking damage are bad usually, except if you can regenerate (with books that heal). Stuff that drop forbidden pickups are bad (evidently), like most sacks, The Relic, etc. Basically orbitals that take up shots are really good. Good items can depend on a lot of things.
You can also pick up the item and instantly stand on the trapdoor, so you can leave the floor before the items can be picked up. Instead of this, try to move away from doors/trapdoors so you can see where the items drop and just avoid them. If you just run out of the room, the drops will be right at the door, so if you need to come back to this room, you could instantly pick up an unwanted pickup, ruining your run. Pickup dropping items: Quite a few Treasure Room / Boss Room items have decent stats but drop forbidden items like Squeezy, Mr. Be careful where you kill pickup dropping champions too. To make your life easier, avoid fires, poops and anything that could drop unnecessary pickups. Otherwise a forbidden pickup might spawn on you and you can start all over again. When you navigate through the floors, make sure that when you clear the room you are not in the center.
If you feel strong enough, and happen to find the boss room faster, you can decide to go for it and leave the room without the Treasure room. You can clear rooms if you have any heal books (mentioned above) to recharge them. Maneuver: Find the treasure room then the boss room. You can do it early game though to check for a possible item and then use Fool to get out. I would avoid chests in Curse rooms, as there is a good probability that blue hearts will drop and slide in front of the exit. Don’t open chest later though, as you might avoid the initial scatter of items, a coin can usually slide in front of the door, ruining the run. Early game I open chest in the first 3-4 floors as the loot is not much and you can pick up a few keys without any trouble of avoiding other pickups.
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